Trazodone (Desyrel) is an antidepressant of the serotonin antagonist and reuptake inhibitor class. It is a phenylpiperazine compound. Trazodone also has anti-anxiety and sleep-inducing effects. Its side-effect profile and potential toxicity are considerably different from those of the original antidepressants (i.e., the monoamine oxidase inhibitors and tricyclic antidepressants). It is available in multiple generic and brand versions. Generic trazodone is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
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Those with depression may begin to notice improvement in symptoms in 1-2 weeks, but in may take 4-6 weeks before the maximum benefit is reached. Some symptoms may improve before others do, and you may have good days and bad days for a few weeks - this is normal progress when recovering from depression.
Therapy is usually started at a total of 150 mg per day divided into two or three doses. This dose is increased by 50 mg every three or four days until the desired effects are seen. Daily doses may be increased to a maximum of 400 mg per day in outpatients and up to 600 mg per day in hospitalized patients. In cases of extreme depression, daily doses of up to 800 mg have been used in hospitalized patients.
Zoloft is the brand name of sertraline, an antidepressant used to treat major depressive disorders (post traumatic stress disorder, panic disorder, obsessive compulsive disorder, social anxiety disorder and premenstrual dysphoric disorder). Zoloft is in a class of antidepressants known as selective serotonin reuptake inhibitors (SSRIs). They work by controlling levels of serotonin in the brain. Zoloft relieves symptoms of depression without the side effects that many people experience with the older tricyclic antidepressants and MAO inhibitors.
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Although some symptoms (sleep, energy or appetite) may improve within a matter of days, it is important to allow four to six or even eight weeks for the medication to be fully effective. If no improvement is seen in two to four weeks, another medication can be tried.
Zoloft is administered once daily by mouth in the morning or evening:
Questions & Answers
You can not buy trazodone and zoloft without prescription in the US, Canada, UK and most other countries in the world. You need to get a prescription for antidepressants from your doctor before being able to access the meds. If you have a prescription, Walgreens, CVS, Walmart or any other online pharmacy will sell drugs for you.
I was prescribed trazadone to help me sleep which it does but it has also helped me tremendously with my depression. This has been good for me. I am having a problem with interaction with Zoloft effecting my eyes. I am going to talk to my doctor about changing my antidepressant.
Trazodone works great for me. I actually only take 50 mg. And get a good 7-8 hours sleep. I'm a diagnosed insomniac. But Trazodone does the job.
I was taking regular Trazodone on and off for a couple of years, it stopped working so my doctor switched me to Desyrel. It's a good pill for the fact that it does make you tired, but I'd make sure you're gonna get 8 or more hours of sleep before you take it. I was prescribed 100mg pills, and I only took half of a pill whenever I took it, and I had the hardest time waking up the next day. Also, with the reg Trazodone and with Desyrel, it took a long time for it to kick in for me (2 hours), but that might be because I have a high tolerance to pills. If you're new to this medicine, take it on the weekend, or whenever you can sleep in, so you can see how it works.
I'm 45 years old and have been on Zoloft for 20 years. I have slowly weaned myself off the drug over the last 12 months. It has now been 2 months without the drug. I am totally debilitated by brain fog, loss of memory, lack of concentration, and irritability. Can anyone please help me with might be happening to me or has anyone been through similar experiences to mine? I'm so upset everyday.... thanks!
I was on Zoloft for about 8 years for severe generalized anxiety disorder and major depressive disorder. I was eventually maxed out (200mg) and I felt awful. I couldn't feel emotions at all, it was almost like depression but less hopeless. I felt like a zombie. Or a robot. I also had pretty severe sexual side effects as well. Got taken off, and I feel like a real human again. I'm on Wellbutrin now.
I was prescribed zoloft in the past and it worked well, so my doctor thought that we should try it again for my anxiety and depression. it worked very well in a short amount of time. it was worth the night sweats to have normal days.