Topamax (Topiramate) is a prescription medication used to treat certain types of seizures in adults and children. It is also used to prevent migraines in patients 12 years of age and older. Topiramate belongs to a group of drugs called anticonvulsants, which decrease abnormal brain activity.
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Topamax affects the activity of two neurotransmitters (natural chemicals that are involved in transmitting messages between the nerve cells) in the brain. Topamax enhances the action of GABA and decreases the action of glutamate. Topamax also works by preventing sodium from entering the nerve cells when they begin to fire rapid and repetitive electrical signals. This prevents the electrical signal from building up and passing on. All three actions help prevent fits.
The half-life of Topamax is reported at 21 hours. This is the time for 1/2 of the amount in the body to be eliminated. Typically - physicians use a period of time equal to 5 or 6 half-lives as a measure of when a drug has cleared. In that case you are in the 4-6 days range.
Topamax is available in tablets (25 mg, 50 mg, 100 mg, and 200 mg) that can be taken orally.
Those who take Topamax typically start with a low dose of 25 or 50 mg per day (divided over two doses), increasing it slowly by 25 to 50 mg per week until an effective daily dose is reached.
Migraine patients are usually given 25 mg every night for the first week, with the dose being increased by 25 mg weekly. The maximum dose is 100 mg, to be taken in two divided doses.
Relpax (Eletriptan) is a prescription medication used to treat migraine headaches once they have started. Eletriptan belongs to a group of drugs called selective serotonin receptor agonists or "triptans", which reduce swelling of blood vessels surrounding the brain.
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Relpax works by stimulating receptors called serotonin (or 5HT) receptors that are found in the brain. A natural substance called serotonin normally acts on these receptors, causing blood vessels in the brain to narrow. Relpax mimics this action of serotonin by directly stimulating the serotonin receptors in the brain. This narrows the blood vessels and so relieves the pain of migraine headaches.
The half-life is about 4 hours. That means half the dose is out of your body in 4 hours. Half of the remaining half is out in the next 4 hours, etc. It takes 6-7 half-lives (24-28 hours) for all of it to be out of the body.
Relpax comes as a tablet to take by mouth. Take one tablet at the first sign of a migraine headache.
If your symptoms improve after you take the drug but return after two hours or longer, you can take a second tablet.
If your symptoms don't improve after the first tablet, call your doctor. Don't take a second tablet before talking with your healthcare provider.
Don't take more than 80 mg of Relpax in 24 hours.
Questions & Answers
You can not buy topamax and relpax without prescription in the US, Canada, UK and most other countries in the world. You need to get a prescription for migraine medications from your doctor before being able to access the meds. If you have a prescription, Walgreens, CVS, Walmart or any other online pharmacy will sell drugs for you.
I was taking Topamax a few years ago for Migraines. I must say I really did lose weight while taking Topamax and I felt great. After taking it about 3 months I noticed that I was becoming depressed. After doing some reading on my insurance carries website, I found that depression is a side effect of Topamax, otherwise it would have been great for me. If you don't have any problems GREAT because it WORKS VERY WELL!
I have been I topamax for 9 weeks and been taking 50 mg daily at night... at the begining of the treatment it did help me prevent the migraines but now it does not. By the time I get up, I wake up with a headache, so am afraid I need to go and see the the dr again.
Topamax made me feel VERY nauseous for the first three months especially but I stuck with it, I did loose weight because of it and I noticed my lack of appetite. Nausea settled a little bit after 3 months, but Topamax did not do a great deal for my migraines which still continued almost just as regularly. For me Relpax has been my saviour. I have migraines and daily headaches and without Relpax my life would be a misery, I nearly missed Christmas and my Daughter Engagement, but thanks to Relpax I didn't, I was miraculously better within an hour and able to have a great time! I am still looking into the genetics behind this. Thank God, I now have a productive life and am able to.
Great! Relpax is a dream come true to me and a nightmare for my migraines! I works within one hour, even when I have a full blown migraine! And my migraine stays GONE!
I suffered for years with migraines, I have lost intire weekends and days from these headaches. Relpax is a life saver, I had times I thought I wanted to die during these headaches. No more, don't have to suffer anymore get the script. It works. Does make you pee alot.