Onglyza vs Januvia


  • Onglyza
  • What is Onglyza

    Onglyza (saxagliptin) is an oral diabetes drugs that helps control blood sugar levels. It works by regulating the levels of insulin your body produces after eating. Saxagliptin is for people with type 2 diabetes. Onglyza is sometimes used in combination with other diabetes medications, but is not for treating type 1 diabetes.

  • Onglyza price

    $ 124.95 (5mg x 28 pills)

    prices from H&B Pharmacy

  • How does onglyza work

    Onglyza is a daily diabetes medication in the class known as gliptins (DPP-4 inhibitors).

    These medicines help to control blood glucose levels by increasing the amount of insulin released by the pancreas and decreasing the body's release of glucagon.

    Saxagliptin is used alone or alongside other oral diabetes drugs.

    These may include metformin, sulfonylurea or a thiazolidinedione.

    Morning blood sugar can rise when you're sleeping, due to the pancreas releasing too much glucagon, which makes the liver release too much sugar. Onglyza (saxagliptin) reduces the amount of sugar released by your liver overnight, which may result in lower blood sugar.

    After-meal blood sugar spikes can occur when your pancreas doesn't release enough insulin or your body's cells do not use insulin properly. Onglyza (saxagliptin) may lower after-meal blood sugar spikes by helping your body increase levels of insulin after meals.

  • How to take onglyza (dosage)

    The usual dose of this medicine is one pill taken once a day. The pills should be swallowed whole and not split or cut.

    The pill can be taken either with or without food at any time of the day. Try to always take your pills at the same time of day, as this will help you remember to take it.

    If you forget to take a dose at your usual time you should take it as soon as you remember. However, if this means taking two doses in one day you should skip the missed dose and continue as normal. Don't take two doses in one day.

  • Side effects

    • Headache;
    • Bloating;
    • Runny or stuffy nose;
    • Sore throat, cough, hoarseness;
    • Nausea, stomach pain, vomiting, or diarrhea;
    • Severe pain in your upper stomach that spreads to your back;
    • Fast heart rate;
    • Painful urination;
    • Swelling of the hands, ankles, or feet;
    • Easy bleeding or bruising;
    • Purple or red skin rash that spreads and causes blistering, or swelling of the face, lips, tongue, or throat.


  • Januvia
  • What is Januvia

    Januvia (Sitagliptin Phosphate) is a once-daily prescription tablet that, along with diet and exercise, helps lower blood sugar levels in adults with type 2 diabetes. Januvia should not be used in patients with type 1 diabetes or with diabetic ketoacidosis. If you have had pancreatitis, it is not known if you have a higher chance of getting it while taking Januvia.

  • Januvia price

    $ 59.95 (25mg x 14 pills)

    prices from H&B Pharmacy

  • How does januvia work

    Januvia works by increasing the amount of two incretin hormones found in the body, called glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP). These hormones are normally produced naturally by the body in response to food intake. Their function is to help control blood sugar levels.

    GLP-1 and GIP have 4 main actions that help to control blood glucose:

    1. They stimulate the pancreas to produce insulin in response to increasing levels of glucose in the blood.
    2. GLP-1 also reduces the production of glucagon.
    3. GLP-1 and GIP reduce the rate at which food passes from the stomach into the intestines, which slows down the absorption of glucose from the gut into the bloodstream.
    4. They act on the brain to cause a feeling of fullness that reduces further food intake.

  • How to take januvia (dosage)

    Take Januvia only when prescribed by your doctor. The recommended dose is to take: one 100 mg pill (once a day) by mouth, with or without food.

    If you have kidney problems, your doctor may prescribe lower doses, and monitor your kidney function.

    Your doctor may prescribe Januvia on its own, or with certain other medicines that lower blood sugar.

    Follow all directions given to you by your pharmacist or doctor carefully. If you do not understand the instructions on the box, ask your pharmacist or doctor for help.

  • Side effects

    • Back pain;
    • Constipation;
    • Diarrhea;
    • Headache;
    • Joint or muscle pain;
    • Little or no urination;
    • Nausea;
    • Severe joint pain;
    • Shortness of breath;
    • Sore throat;
    • Stomach pain;
    • Stuffy or runny nose;
    • Weight gain.

Questions & Answers

Where to buy onglyza or januvia over the counter in the U.S.?

You can not buy onglyza and januvia without prescription in the US, Canada, UK and most other countries in the world. You need to get a prescription for diabetes pills from your doctor before being able to access the meds. If you have a prescription, Walgreens, CVS, Walmart or any other online pharmacy will sell drugs for you.



I'm currently taking Onglyza for my type 2 diabetes once a day. My levels have not really decreased. I am still in the range of 7.5 to 8... My diet is right on target and so are my exercise routines... I can't inject or test monitor/lancet. I am not going to continue to increase my pill intake by another pill form medication. What does one do?


Blood glucose was well within acceptable ranges for 4-6 weeks, after that they began to graduaolly increase. The whole time I have been taking this I have had multiple (6-8 times a day) incidences of complete whole body drenching sweating. This is enough to cause be to seek another drugs. I will call the dr seeking an alternative medication.


I'm taking Onglyza with Lantus. It took about two weeks for the headache to do away but other than that, it's great and no side effects except one for which I'm grateful. All the weight put on by the Lantus (117 lbs) is starting to come off slowly but steadily.


I am a chronic pain patient as well as a type two diabetic, so I don't really know if it's the Januvia or my back causing this, but since taking it, my feet feel like they are frozen in blocks of ice, yet they are not really cold. I'm wearing 3 heavy pairs of socks yet they are still cold "feeling".


I used Januvia for a month and a half. It worked well at first. Then my right knee swelled, my left foot I could not walk on. When I stopped taking Januvia swelling went away. It worked well at controlling my blood sugar levels, but too much pain. Oh... I never injured my knee or foot.

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