Januvia vs Actos


  • Januvia
  • What is Januvia

    Januvia (Sitagliptin Phosphate) is a once-daily prescription tablet that, along with diet and exercise, helps lower blood sugar levels in adults with type 2 diabetes. Januvia should not be used in patients with type 1 diabetes or with diabetic ketoacidosis. If you have had pancreatitis, it is not known if you have a higher chance of getting it while taking Januvia.

  • Januvia price

    $ 59.95 (25mg x 14 pills)

    prices from H&B Pharmacy

  • How does januvia work

    Januvia works by increasing the amount of two incretin hormones found in the body, called glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP). These hormones are normally produced naturally by the body in response to food intake. Their function is to help control blood sugar levels.

    GLP-1 and GIP have 4 main actions that help to control blood glucose:

    1. They stimulate the pancreas to produce insulin in response to increasing levels of glucose in the blood.
    2. GLP-1 also reduces the production of glucagon.
    3. GLP-1 and GIP reduce the rate at which food passes from the stomach into the intestines, which slows down the absorption of glucose from the gut into the bloodstream.
    4. They act on the brain to cause a feeling of fullness that reduces further food intake.

  • How to take januvia (dosage)

    Take Januvia only when prescribed by your doctor. The recommended dose is to take: one 100 mg pill (once a day) by mouth, with or without food.

    If you have kidney problems, your doctor may prescribe lower doses, and monitor your kidney function.

    Your doctor may prescribe Januvia on its own, or with certain other medicines that lower blood sugar.

    Follow all directions given to you by your pharmacist or doctor carefully. If you do not understand the instructions on the box, ask your pharmacist or doctor for help.

  • Side effects

    • Back pain;
    • Constipation;
    • Diarrhea;
    • Headache;
    • Joint or muscle pain;
    • Little or no urination;
    • Nausea;
    • Severe joint pain;
    • Shortness of breath;
    • Sore throat;
    • Stomach pain;
    • Stuffy or runny nose;
    • Weight gain.


  • Actos
  • What is Actos

    Actos (Pioglitazone Hydrochloride) is one of six types of diabetes pills currently used to treat type 2 diabetes. It will help keep your blood glucose levels within your target range by making your body more sensitive to insulin. It is not for use in treatment of Type 1 diabetes or diabetic ketoacidosis. Actos Is available as a generic drug. You need a prescription for Actos.

  • Actos price

    $ 44.95 (15mg x 30 pills)

    prices from H&B Pharmacy

  • How does actos work

    • Actos improves how the body uses insulin.
    • Actos decreases the amount of glucose released by the liver.
    • Actos does not cause the body to make more insulin, therefore, when used alone, it does not cause low blood glucose (hypoglycemia).

    Guidelines for use:

    • Actos can be taken with or without food.
    • Some medications similar to Actos have caused liver problems. Although Actos has not been associated with liver problems, your healthcare provider will check your liver function prior to your using the medication and then every two months for the first year.
    • To further improve your blood glucose control, your healthcare provider may have you use Actos in combination with another diabetes pill or with insulin.

  • How to take actos (dosage)

    Actos comes as a tablet and is typically taken by mouth once a day, with or without meals.

    Your dosage will be based on your medical condition, response to treatment, and other drugs you're taking.

    Try to take pioglitazone around the same time each day.

    Your doctor might start you on a low dose and gradually increase it.

    Follow the instructions on your prescription label carefully. Don't take more or less than is prescribed.

  • Side effects

    • Headache;
    • Sore throat;
    • Gas;
    • Sinus pain;
    • Stomach pain, loss of appetite;
    • Swelling or rapid weight gain;
    • Tooth problems;
    • Pain in the arms or legs;
    • Vision changes or vision loss;
    • Discolored, cloudy, or bloody urine;
    • Back or abdominal pain;
    • Feeling short of breath, even with mild exertion.

Questions & Answers

Where to buy januvia or actos over the counter in the U.S.?

You can not buy januvia and actos without prescription in the US, Canada, UK and most other countries in the world. You need to get a prescription for diabetes pills from your doctor before being able to access the meds. If you have a prescription, Walgreens, CVS, Walmart or any other online pharmacy will sell drugs for you.



I am a chronic pain patient as well as a type two diabetic, so I don't really know if it's the Januvia or my back causing this, but since taking it, my feet feel like they are frozen in blocks of ice, yet they are not really cold. I'm wearing 3 heavy pairs of socks yet they are still cold "feeling".


I used Januvia for a month and a half. It worked well at first. Then my right knee swelled, my left foot I could not walk on. When I stopped taking Januvia swelling went away. It worked well at controlling my blood sugar levels, but too much pain. Oh... I never injured my knee or foot.


I don't care what the FDA said when they put this drug back on the market... I have spoken to many oncologists in major hospitals and they have no doubt that 4 years of Actos caused my bladder cancer. Shame on the FDA for giving in to pressure once again.


I was on actos for about 6 months and experienced unexplained fatigue, weight gain, fluid retention, shortness of breath and (the last straw that broke the camel's back) Congestive Heart Failure-CHF in Dec '15. Then when I reported the CHF to my Endocrinologist on Jan 9 she said it was the actos and immediately took me off (the actos). I'm humbly advising all and sundry to stay away from this drug for it will damage you slowly.

Add review