Onglyza (saxagliptin) is an oral diabetes drugs that helps control blood sugar levels. It works by regulating the levels of insulin your body produces after eating. Saxagliptin is for people with type 2 diabetes. Onglyza is sometimes used in combination with other diabetes medications, but is not for treating type 1 diabetes.
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Onglyza is a daily diabetes medication in the class known as gliptins (DPP-4 inhibitors).
These medicines help to control blood glucose levels by increasing the amount of insulin released by the pancreas and decreasing the body's release of glucagon.
Saxagliptin is used alone or alongside other oral diabetes drugs.
These may include metformin, sulfonylurea or a thiazolidinedione.
Morning blood sugar can rise when you're sleeping, due to the pancreas releasing too much glucagon, which makes the liver release too much sugar. Onglyza (saxagliptin) reduces the amount of sugar released by your liver overnight, which may result in lower blood sugar.
After-meal blood sugar spikes can occur when your pancreas doesn't release enough insulin or your body's cells do not use insulin properly. Onglyza (saxagliptin) may lower after-meal blood sugar spikes by helping your body increase levels of insulin after meals.
The usual dose of this medicine is one pill taken once a day. The pills should be swallowed whole and not split or cut.
The pill can be taken either with or without food at any time of the day. Try to always take your pills at the same time of day, as this will help you remember to take it.
If you forget to take a dose at your usual time you should take it as soon as you remember. However, if this means taking two doses in one day you should skip the missed dose and continue as normal. Don't take two doses in one day.
Metformin (Glucophage Xr) is an inexpensive medicine used to treat high blood sugar levels caused by type 2 diabetes. It is is more popular than comparable drugs. It is available in both brand and generic versions. Generic metformin is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.
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Metformin works in a number of ways to lower blood sugar levels in people with type 2 diabetes.
Patients also tend to see their cholesterol levels drop and an increase in sensitivity to insulin. Some metformin users lose weight because of the drug's affect on appetite, naturally leading the patient to eat fewer calories!
For the first week of treatment you will usually be asked to take 500mg metformin once a day.
After this, your dose may be gradually increased, either by taking the medicine two and then three times a day, or by taking higher strength tablets. It's important that you always follow the instructions given by your doctor. These will be printed on the dispensing label that your pharmacist has put on the medicine. If you are unsure about anything, ask your doctor or pharmacist for advice.
All forms of metformin should be taken with a meal or a snack.
I'm currently taking Onglyza for my type 2 diabetes once a day. My levels have not really decreased. I am still in the range of 7.5 to 8... My diet is right on target and so are my exercise routines... I can't inject or test monitor/lancet. I am not going to continue to increase my pill intake by another pill form medication. What does one do?
Blood glucose was well within acceptable ranges for 4-6 weeks, after that they began to graduaolly increase. The whole time I have been taking this I have had multiple (6-8 times a day) incidences of complete whole body drenching sweating. This is enough to cause be to seek another drugs. I will call the dr seeking an alternative medication.
I'm taking Onglyza with Lantus. It took about two weeks for the headache to do away but other than that, it's great and no side effects except one for which I'm grateful. All the weight put on by the Lantus (117 lbs) is starting to come off slowly but steadily.
Been taking 1000 mg twice a day for almost 9 years along with Lantus. Metformin messed with my stomach, etc., for about 2-3 weeks, but no adverse events since then.
I love Metformin - oral contraceptives never helped me and only Metformin has been able to help control my PCOS symptoms. It took about 6 months for me to see any real benefits and then I noticed that the benefits were incredible. I have lost a lot of weight, and I just wanted to offer a word of caution. Please continue to go to your doctor and monitor your progress. Metformin (although I love it) is a pretty serious drug with major side effects. As you lose weight, your dose may need adjusting as mine did. I went from 2000mg a day to years ago down to 500 over those two years!
I had some initial weight loss from metformin. I think it was in part due to having diarrhea initally, a slightly diminshed appetite and a sort of metallic taste. All those side effects went away though.