Venlafaxine, also known by its trade name as Effexor, is an antidepressant. It is used for the treatment of major depressive disorder and anxiety disorders, and specifically for generalized anxiety disorder and social anxiety disorder. Physicians are becoming more likely to prescribe Effexor to treat other symptoms and conditions as well. Since Effexor works by regulating serotonin and norepinephrine levels in the brain, it can effectively help treat pain caused by severe migraines and diabetic neuropathy. This tablets is available on prescription only.
$ 23.35 (Package 37.5mg x 30 pills)
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While symptoms of depressed mood and lack of interest in activities may need up to 4-6 weeks to improve; disturbances in sleep, appetite or energy may show some improvement within the first 1-2 weeks. Improvement in these physical symptoms can be an important early signal that the medication is working.
Effexor comes in immediate-release tablets of 25 mg, 37.5 mg, 50 mg, 75 mg, and 100 mg, and in extended-release capsules of 37.5 mg, 75 mg, 150 mg, and 225 mg. If taken as an immediate-release pill, the dose is usually split up and taken two or three times during the day, with food. If you're taking the extended-release capsules, take your dose at breakfast or dinner, ideally at the same time every day. You need to swallow the capsule whole: do no crush, chew or place it in a liquid.
Nortriptyline is a second-generation tricyclic antidepressant marketed as the hydrochloride salt under the trade names Aventyl and Pamelor. It is used in the treatment of major depression and childhood nocturnal enuresis. Its off-label uses include treatment of chronic fatigue syndrome, chronic pain and migraine, and labile affect in some neurological disorders. It may also be used to help people quit smoking and to treat attention deficit hyperactivity disorder. Nortriptyline comes as a capsule and an oral liquid to take by mouth.
$ 41.95 (Package 25mg x 30 pills)
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Every patient is different. You may notice some initial benefit within 2 weeks, however it may take up to 2 months for a full effect. Your doctor may need to increase the dose to get the maximum effect. If you do not feel any improvement in your pain after 2 months, do not suddenly stop taking the tablets but speak to your doctor.
Usual adult dose - 25 mg three or four times daily; dosage should begin at a low level and be increased as required. As an alternative regimen, the total daily dosage may be given once a day. When doses above 100 mg daily are administered, plasma levels of nortriptyline should be monitored and maintained in the optimum range of 50 to 150 ng/mL. Doses above 150 mg/day are not recommended.
My physician started me out on 37.5 mg/day for 1 week then increased the dosage to 75 mg/day for another week and, finally, to 150 mg/day. After taking 150 mg/day for about a week, I felt it was too much... my heart was always racing, I couldn't sleep, and I generally just felt "nervous". My physician dropped my dosage back to 75 mg/day and that seemed to work best for me. I absolutely feel that the Effexor helped lift my depression. However, I eventually chose to stop taking it because of the sexual side effects. After being on Effexor for about a year, I both wanted and needed to have a healthy sexual relationship with my husband again. I dropped the dosage back to 37.5 mg/day for a week, then one every other day for about another week before stopping altogether. I don't recall having any "withdrawal" symptoms. Within a few days of the last dose, all sexual functions were back.
Effexor helped me immensely with pulling out of a very long/recurrent depression. I think I started at 75mg, and had mild side effects that pretty much went away. Some people cant tolerate it at all, but if you can, it can be very effective. I maxed out at 450mg for something like 6 months and while it was great for my depression, it never helped with my anxiety problems. After my first several-days-long hypomanic episode though I'm rediagnosed bipolar ii and coming off effexor. And thats where most of the effexor horror stories start - a lot of us get withdrawal symptoms. I had no problems tapering back down to 150 but get "the zaps" and nausea etc below that. But there are ways to manage and reduce it. Overall, even though the med has some downsides, its definitely been a positive experience for me.
Nortriptyline has helped with my constant headache and has also helped me cope with my stress/anxiety. I'm on a low dose (20mg/day) and take at night. The first week I was out cold within minutes of taking the medication. That affect has worn off, but I continue to sleep well and wake up refreshed.
This med is amazing. I've had peripheral Neuropathy for a few years in my feet. I've tried Gabapentin, it didn't work. I tried Nortriptyline, I've been on it for 3-4 weeks...it's amazing... NO pins/needles feeling, no burning sensation! I still have some pressure in my feet, but things are so different now! I'm going to give it more time, but I think I found my holy grail! I understand it may not work for everyone, but so far it's working for me. If you are looking for something, ask your doctor and try it, it might work for you. Good luck to all of you!