Demadex (torsemide) is a loop diuretic (water pill) that prevents your body from absorbing too much salt, allowing the salt to instead be passed in your urine. Demadex treats fluid retention in people with congestive heart failure, liver disease, and kidney disorder. It also used to treat high blood pressure.
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Demadex acts from within the lumen of the thick ascending portion of the loop of Henle, where it inhibits the Na+/K+/2CI--carrier system. Effects in other segments of the nephron have not been demonstrated. Diuretic activity thus correlates better with the rate of drug excretion in the urine than with the concentration in the blood. Demadex increases the urinary excretion of sodium, chloride, and water, but it does not significantly alter glomerular filtration rate, renal plasma flow, or acid-base balance.
Congestive heart failure: the standard starting dose is 10 or 20 mg taken by mouth once per day. The maximum dose is 200 mg per day.
Kidney failure: The standard starting dose is 20 mg taken by mouth once per day. The maximum dose is 200 mg per day.
Liver disease: The standard starting dose is 5 or 10 mg taken by mouth once per day. The maximum dose is 40 mg per day.
Hypertension: The usual initial dose is 5 mg once daily. If the 5 mg dose does not provide adequate reduction in blood pressure within 4 to 6 weeks, the dose may be increased to 10 mg once daily.
Diamox pills contain the active ingredient acetazolamide, which is a type of medicine called a carbonic anhydrase inhibitor. Its main use is in treating glaucoma, which is a condition where the pressure inside the eyeball is too high. Diamox also used to treat or prevent symptoms of mountain sickness.
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An increase in pressure within your eye can lead to damage to the optic nerve at the back of your eye. When this occurs it is called glaucoma. Glaucoma can lead to a loss of vision if it is not treated. Treatment with Diamox helps to reduce eye pressure, and this helps to prevent further eye damage. Diamox works by blocking the action of an enzyme called carbonic anhydrase. Blocking this enzyme reduces the amount of fluid (called aqueous humour) that you make in the front part of your eye, and this helps to lower the pressure within your eye.
Glaucoma: the recommended dose range for Diamox is 250 mg-1000mg/day.
Acute Mountain Sickness: the recommended dose range for Diamox is 500 mg-1000mg/day.
Edema: recommended dosage is 250 to 375 mg of acetazolamide once a day for one or two days, alternating with a day of rest.
Diuresis in Congestive Heart Failure: the starting dose is usually 250 to 375 mg once daily in the morning.
Epilepsy: the recommended dose range for Diamox is 375 to 1000 mg daily.
I had been using lasix 40mg for a couple of years to control my water retention BUT it caused my blood sodium levels to drop to critical level and put me in the hospital for 11 days, but I'm using demadex now and it works for me with no other problems.
I was prescribed with Demadex (torsemide) to treat my high blood pressure. I live with hypertension since I remember myself and it really affects my lifestyle and my career. With Demadex the quality of my life is much higher as I know that I take a drug that I can rely on and it won't give me up when I do not expect it. Demadex is a life saver for me and I thank the people who have invented this med!
I have been recently diagnosed with the disease called BIH which occurs mostly in women and very young children and currently taking Diamox with annoying side effects such as pins and needles in feet, hands and lips which can last up to 2 hours at a time and be painful. I wake every night with interrupted sleep with a headache or temperature! I have been turned off a lot of food but mainly fizzy drinks.
The dose of acetazolamide for prophylaxis is 125-250 mg twice a day starting 24 hours before ascent, and discontinuing after the second or third night at the maximum altitude (or with descent if that occurs earlier). Sustained release acetazolamide, 500 mg, is also available and may be taken once per day instead of the shorter acting form, though side effects will be more prominent with this dose.