Amitriptyline is a prescription drug that's used to treat depression. It's sometimes known by its former brand name, Elavil, but its manufacturer, AstraZeneca, stopped making it. Amitriptyline is only available as a generic drug in the United States. Besides depression, amitriptyline can be used "off-label" to treat post-herpetic neuralgia, attention deficit hyperactivity disorder, and certain eating disorders. It may also be used to prevent symptoms of migraines. It is in the tricyclic antidepressant class and its exact mechanism of action is unclear. Amitriptyline is taken by mouth.
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In depression it may take between 1 to 4 weeks before amitriptyline starts to work and you begin to feel better. Usually recommend continuing antidepressants for at least six months after recovery. With nerve pain amitriptyline may start to help in a few days for some people, while others don't see much difference for 1-2 weeks.
Usual adult dose for depression: 75 mg orally per day in divided doses; this may be increased to a total of 150 mg per day if needed.
Alternate dose: 40 to 100 mg orally as a single dose at bedtime; this may be increased by 25 or 50 mg as needed at bedtime to a total of 150 mg per day.
Maximum dose: 150 mg orally per day.
Zoloft is the brand name of sertraline, an antidepressant used to treat major depressive disorders (post traumatic stress disorder, panic disorder, obsessive compulsive disorder, social anxiety disorder and premenstrual dysphoric disorder). Zoloft is in a class of antidepressants known as selective serotonin reuptake inhibitors (SSRIs). They work by controlling levels of serotonin in the brain. Zoloft relieves symptoms of depression without the side effects that many people experience with the older tricyclic antidepressants and MAO inhibitors.
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Although some symptoms (sleep, energy or appetite) may improve within a matter of days, it is important to allow four to six or even eight weeks for the medication to be fully effective. If no improvement is seen in two to four weeks, another medication can be tried.
Zoloft is administered once daily by mouth in the morning or evening:
I wasn't prescribed 10mg of amitriptyline for migraines and to help me sleep. This drug is great for helping you sleep. I was drowsy within 10 mins of taking it at night before bed. However, as a migraine prophylactic it did not help. I had migraines occurring frequently and often worse than they were prior to starting this medication. I also gained 18 lbs in 4 months. My breasts became very swollen and tender and I ended up extremely depressed. My dosage was the lowest you can get. I cannot even imagine taking more than I did and the side effects it would have had. I don't recommend this to anyone.
I have had insomia for months. Dr started me on Elavil 10mg for sleep, within a half hour I'm a sleep. I have not slept this good in a long time. I am not a zombie either in the mornings. I feel very good when I awake. Best thing.
If I take amitriptyline in the morning, I am so tired that functioning and performing even small tasks is very difficult. But if I take it too late at night, I have really bad nightmares. So find a time that works best for you.
I'm 45 years old and have been on Zoloft for 20 years. I have slowly weaned myself off the drug over the last 12 months. It has now been 2 months without the drug. I am totally debilitated by brain fog, loss of memory, lack of concentration, and irritability. Can anyone please help me with might be happening to me or has anyone been through similar experiences to mine? I'm so upset everyday.... thanks!
I was on Zoloft for about 8 years for severe generalized anxiety disorder and major depressive disorder. I was eventually maxed out (200mg) and I felt awful. I couldn't feel emotions at all, it was almost like depression but less hopeless. I felt like a zombie. Or a robot. I also had pretty severe sexual side effects as well. Got taken off, and I feel like a real human again. I'm on Wellbutrin now.
I was prescribed zoloft in the past and it worked well, so my doctor thought that we should try it again for my anxiety and depression. it worked very well in a short amount of time. it was worth the night sweats to have normal days.