Aldactone (spironolactone) is a prescription diuretic used to remove the excess fluid caused by congestive heart failure, cirrhosis of the liver, and kidney disease. It also can be used in combination with other drugs to treat elevated blood pressure, and for treating diuretic-induced low potassium.
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Aldactone works by blocking the actions of a hormone in the body called aldosterone. Aldosterone is a hormone that causes the body to retain water. By blocking it, Aldactone increases the amount of salt and water the kidneys remove from the blood. This extra salt and water is passed out through urine. By increasing the amount of water removed from the blood, Aldactone causes a decrease in blood volume. Because of this effect, the medication can lower blood pressure and also help with water retention.
For fluid retention in conditions such as congestive heart failure, cirrhosis of the liver, or kidney disorders, the usual starting dosage is 100 mg daily either in a single dose or divided into smaller doses. In some cases, your doctor may have you take a daily dose as low as 25 mg or as high as 200 mg.
When potassium loss can't be treated with a potassium supplement, your doctor may have you start with a daily dosage between 25 and 100 mg of Aldactone.
For essential hypertension the usual starting dosage is 50 to 100 mg daily in a single dose or divided into smaller doses.
Lasix (furosemide) is in a class of medications called diuretics or "water pills". It helps you make more urine and to lose salt and excess water from your body. This medicine is used to treat high blood pressure, and edema or swelling from heart, kidney or liver disease.
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In the kidneys, salt, water, and other small molecules normally are filtered out of the blood and into the tubules of the kidney. The filtered fluid ultimately becomes urine. Most of the sodium, chloride and water that is filtered out of the blood is reabsorbed into the blood before the filtered fluid becomes urine and is eliminated from the body. Lasix works by blocking the absorption of sodium, chloride, and water from the filtered fluid in the kidney tubules, causing a profound increase in the output of urine.
Your doctor will decide what dose you should take based on your condition and medical history. Never stop taking Lasix or alter your dose without your doctor's approval.
Adults who have fluid retention problems will typically begin with a single dose of 20 milligrams to 80 mg. The dose in children will vary based on what your doctor deems appropriate.
Adults who have high blood pressure often begin with 40 mg, twice per day. The dosage may be adjusted for elderly patients.
My review is solely on the side effects I've been experiencing since I began taking Aldactone, 1 week ago. I was prescribed 50 mg, once a day, Spiro for adult acne by my derm. I cannot vouch to whether or not it is helping my acne. As of yet I don't see improvement, however I understand that part takes time. The side effects currently have me at the edge of withdrawing taking this medicine entirely. My side effects have been foggy brained, shakiness, fatigued, spaced out, restlessness, lots of thirst, frequent urinating, unusual heart beat and headaches. I have noticed that if I drink coffee these symptoms are WORSE. Hoping to have some of these side effects lessen or I will have to throw in my towel on Aldactone.
The increase in hair shedding is a normal, Temporary, side effect of Aldactone (spironolactone). As your hormones adjust the shedding will stop. I have been taking aldactone at 25mg daily for about 1 year, and my skin is now completely oil free, and I have noticed a dramatic decrease in the amount of break outs that I get.
My wife (52 years old) started furosemide 20 mg twice a day for fluid retention. It has helped with that, but has caused hearing loss in both ears. She has been told to stop for two weeks and see her doctor for blood work afterwards.
I have been taking Lasix for a long time due to hypertension. I have a lot of problems with swollen hands, especially in the mornings. I am very sensitive to salt. I have to be careful taking it when I am working because for the first few hours I am there, I usually have to go to the restroom several times, but then it levels off in the afternoon. I also started Wellbutrin which also has a diuretic effect, so taking both of them sometimes gets a little out of hand!
I have been using Lasix in combination with Hydrochlorothiazide for 6 months for pitting edema/hypertension and it's effects seem to have worn off. I started on 20mg once a day for 2 months then up to 40mg once a day for the last 4 months. Now my legs are back to swelling as much as if I were taking nothing. My blood pressure is good though. Side effects, headaches.